Review of the top 3 Integration Engines

Comparing: Rhapsody, Cloverleaf, and HealthShare

In the healthcare IT landscape, integration engines are indispensable for facilitating smooth data transfer among diverse systems. This blog post will provide a comparative analysis of three leading integration engines: Rhapsody, Cloverleaf, and HealthShare, highlighting their unique strengths and variances.

Rhapsody Integration Engine

Rhapsody, a healthcare-centric integration engine, is widely utilized by a variety of entities including public and private hospitals, health systems, Health Information Exchanges (HIEs), vendors, public health departments, and federal government organizations. It is engineered to simplify data exchange and promote efficient interoperability. Its key features encompass flexibility in data flow, global deployment capability, support for FHIR-based interfaces with REST and FHIR-specific JSON support, along with inherent security measures.

Rhapsody supports FHIR messaging and can be used to build FHIR interfaces. It is developer-friendly and based on internet standards used in other industries, lowering the barrier to entry for developers to create solutions that support patient care while not over-burdening their health system clients.

Rhapsody can transform any standard to FHIR and FHIR to any standard with Corepoint Integration Engine or Rhapsody Integration Engine. It can receive data in other ways, such as via CSV files, HL7 V2, SQL, proprietary APIs, and more and then transform it to the required version of FHIR to send outbound.

Rhapsody provides a developer-friendly environment for understanding and testing FHIR APIs, using a Swagger-UI front-end, and easy access to all FHIR search parameters and documentation.  Rhapsody API Gateway provides native FHIR integration and FHIR handling backed by a best-in-breed FHIR server, providing a single API entry point to control and secure all traffic.

Cloverleaf Integration Suite

Cloverleaf serves as a top-tier interoperability engine tailored for the contemporary healthcare enterprise. It is adopted by over a third of US hospitals and has a presence in 36 countries. Cloverleaf enhances the exchange of clinical data to boost healthcare outcomes and operational efficiency. It is scalable to accommodate healthcare organizations of all sizes, supports the latest standards (including HL7 FHIR), and is recognized for its robustness, scalability, flexibility, and reliability.

Infor Cloverleaf FHIR Server is a solution that allows healthcare organizations to extend their electronic health records (EHR) and clinical systems’ FHIR and application programming interface (API) capabilities beyond their current support.

It enables you to streamline care coordination by providing the right amount of needed information to providers and patients, expedite your organization’s digital transformation while utilizing your existing clinical systems connected to an innovative FHIR-based ecosystem.

Infor Cloverleaf FHIR Server is built on the HL7 FHIR standard and makes data available using the modern API to store and exchange data.

HealthShare Integration Engine

HealthShare Health Connect is an integration engine that provides high-volume transaction support, process management, and continuous monitoring essential for the round-the-clock business of healthcare. It adheres to standards and profiles necessary for interoperability and document-based health information exchange with other healthcare organizations, clinicians, and public health agencies. It offers extensive support for FHIR® interoperability and equips an interface engineer with all the necessary tools to handle FHIR requests.

InterSystems FHIR Server is a cloud-based, enterprise-grade FHIR server that provides an easy-to-use, secure, and scalable repository for storing and sharing healthcare data. It is built on InterSystems IRIS for Health, which is known for its high performance, scalability, and reliability.

The server supports the latest HL7 FHIR version, including the United States Core Data for Interoperability (USCDI), and the UK Core Open API-based definitions for all FHIR resources, making it easy for you to query and test your FHIR server. InterSystems FHIR Server provides a developer portal for understanding and testing FHIR APIs, using a Swagger-UI front-end, and easy access to all FHIR search parameters and documentation.

It also offers full lifecycle FHIR API management, multiple methods of authentication, including an API Key and several Identity Providers (iDPs) using OpenID Connect, and built-in support for OAuth 2.0 using the Cognito authorization server, including intuitive methods to select custom FHIR scopes.

InterSystems FHIR Server is built on AWS ISO 27001 and HITRUST certified infrastructure to support HIPAA* and GDPR** and is managed by InterSystems Managed Services through processes developed using the HITRUST Common Security Framework.


When comparing Rhapsody, Cloverleaf, and HealthShare, all three have a strong presence in the healthcare sector with customers in 36 countries. They all support the latest standards like HL7 FHIR and prioritize security. However, they might differ in their user interface, ease of use, customer support, and specific functionalities. For a more detailed comparison tailored to your specific needs, you might want to consider factors such as cost, scalability, ease of use, customer support, community reviews, and more.


In conclusion, the choice between Rhapsody, Cloverleaf, and HealthShare hinges on your specific needs and requirements. All three are robust solutions that can significantly enhance data interoperability in healthcare settings.